Results displayed in this PheWeb include genome-wide associations from 145,490 participants in Taiwan Biobank. All individuals were gentoyped on the Axiom Genome-Wide TWB Array or Axiom Genome-Wide TWB2.0 Array. The genotype data were then imputed using a mereged reference panel consisting of East Asian population from 1000 Genomes phase 3 (n=504) and whole-genome sequencing data from Taiwan Biobank (n=1,451) by IMPUTE2 software.
Associations were conducted using SAIGE software with adjustment for age, sex, BMI, genotyping array, and top 5 principal components (The height, weight, and BMI phenotypes were adjusted for age, sex, genotyping array, and top 5 principal components). We processed a set of 242 phenotypes including 111 quantitative traits as well as 131 binary traits with at least 100 cases. Genetic correlations were estimated across phenotypes with heritability z score > 2 by LDSC using East Asian LD scores from 1000 Genomes Project phase 3.
All positions are on GRCh38.
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